Intrauterine Insemination (IUI)

A basic infertility treatment method that involves selecting healthy, motile sperm and placing them directly into the uterus during ovulation to increase the chances of sperm reaching the egg.

About

What is IUI?

IUI (Intrauterine Insemination) is an assisted reproductive technology in which sperm from the male partner is processed in a laboratory to select the most healthy, strong, and motile sperm.
The selected sperm is then placed directly into the woman’s uterus on the day of ovulation, reducing the distance sperm must travel and increasing the chance of fertilization.

IUI Treatment

Suitable for couples who wish to begin infertility treatment with a simple, minimally invasive, and time-efficient method that closely resembles natural conception.

  • 1

    Procedure takes approximately 15–30 minutes

  • 2

    No surgery required and minimal recovery time

  • 3

    Pregnancy test results available in about 2 weeks

Why IUI

Why is IUI a common first-line treatment for infertility?

IUI is a less complex procedure compared to IVF or ICSI, as fertilization still occurs inside the female body. It helps sperm reach the fallopian tubes more easily at the optimal time for fertilization.
This method is suitable for cases where basic fertility factors are still favorable, such as regular ovulation, healthy fallopian tubes, and adequate sperm quality after laboratory processing.

10–15%

General success rate

The success rate of IUI depends on factors such as the woman’s age, egg quality, fallopian tube condition, uterine health, and the quality of processed sperm.

Process

IUI Procedure

IUI begins with health evaluation, ovulation monitoring, sperm preparation, and insemination into the uterus at the optimal time.

  • 1

    Preparation and Health Assessment

    Both partners undergo health checks and receive guidance on physical and mental preparation before starting IUI treatment.

  • 2

    Ovulation Monitoring

    Ovulation is monitored using LH hormone test kits or ultrasound to identify the most suitable timing.

  • 3

    Ovarian Stimulation

    In some cases, the doctor may prescribe ovarian stimulation medication to increase the number of mature eggs, followed by an ovulation trigger injection and scheduling of the IUI procedure.

  • 4

    Sperm Collection and Preparation

    The male partner provides a semen sample on the day of treatment. Embryologists then select the healthiest, most motile sperm.

  • 5

    Intrauterine Insemination

    A catheter is gently inserted through the cervix to place the prepared sperm directly into the uterus.

  • 6

    Pregnancy Testing

    After the procedure, pregnancy is tested approximately 2 weeks later.

Success Factors

Factors Affecting the Success of IUI

The success of IUI depends on both male and female factors. The doctor will evaluate suitability before planning treatment.

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The male partner should have at least around 1 million motile sperm after sperm processing

The female partner should have healthy, non-blocked, and functional fallopian tubes

The woman’s age should not be too advanced, as age affects egg quality

No severe cervical abnormalities that may interfere with insemination
No uterine conditions that may affect fertilization or implantation
A healthy and appropriately thick endometrial lining suitable for implantation

Aftercare

Post-IUI Care Instructions

After intrauterine insemination, patients should follow the doctor’s advice, especially during the first few days, to support the body for fertilization and embryo implantation.

Rest for about 30 minutes after the procedure

After IUI, patients are advised to lie still and rest to help support sperm movement toward the egg.

Avoid sexual intercourse in the early period

Refrain from sexual intercourse for the first 1–2 days to avoid disturbing the uterus.

Avoid strenuous activities

Refrain from heavy work, lifting heavy objects, or intense exercise during the recovery period.

Maintain proper nutrition and rest

Eat nutritious foods, get adequate sleep, and reduce stress.

Who Should Consider

Who is suitable for IUI?

Male Partner

Erectile dysfunction or premature ejaculation

Difficulty maintaining an erection

Mild to moderate issues with sperm quality or quantity

Poor sperm motility, but still sufficient for laboratory selection

Female Partner

Ovulation problems or chronic anovulation, such as PCOS

Certain types of infertility, such as endometriosis

Mild cervical or uterine abnormalities that are not severe

Planning pregnancy using previously frozen sperm samples

Benefits

Advantages of IUI

b1

IUI is a basic treatment for infertility that closely resembles natural conception. It is simple, not complicated, and less invasive than other methods.

b2

It can be performed in every menstrual cycle and is relatively affordable.

b3

It helps determine the optimal timing for pregnancy, allowing conception and childbirth when you are ready and at the most appropriate time.

b4

It does not involve surgery. It is simply the injection of sperm from the male partner into the female uterus. After IUI, no recovery time is required.

Comparison

How is IUI different from GIFT, IVF, and ICSI?

IUI

Sperm is selected and then placed into the uterus during ovulation to allow fertilization to occur inside the body.

GIFT

Eggs and sperm are placed into the fallopian tube to allow natural fertilization, but the procedure requires surgery and a longer recovery period.

IVF

Eggs and sperm are combined outside the body in a laboratory. The resulting embryos are then cultured and transferred back into the uterus.

ICSI

A selected sperm is directly injected into an egg in the laboratory. It is suitable for cases that require greater control over fertilization.

Medical Note

Is IUI suitable for everyone?

IUI is not suitable for all cases. If there is severe fallopian tube blockage, very poor sperm quality, advanced maternal age, or repeated unsuccessful IUI cycles, the doctor may recommend other treatments such as IVF or ICSI to improve the chances of success.

Consultation

Consult IUI Treatment with a Fertility Specialist

If you would like to assess your suitability for intrauterine insemination (IUI) or plan infertility treatment, you can contact Gift Fertility Centre Bangkok for an initial consultation and professional guidance.

FAQ

Frequently Asked Questions about IUI

Is IUI painful?

How long does IUI take?

Are there any side effects of IUI?

Is IUI safe?

Are there any limitations for IUI?

What are the possible complications of IUI?

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